The Correlation between Low Birth Weight and the Degree of Neonatal’s Kidney Function Impairment in RSUDZA

Cut Zahara Phoenna, Dora Darussalam, Syafruddin Haris, Sulaiman Yusuf, Heru Noviat Herdata, Bakhtiar Bakhtiar

Abstract


Low birth weight (LBW) is often found in premature birth or because of early gestational age. Several studies have evaluated the impact of Acute Kidney Injury (AKI) on neonates. Birth weight is an important predictor of the nephron and glomerular mass. Mortality in infants with AKI is significantly higher than in those without AKI. Objectives: To analyze the correlation between birth weight and the degree of kidney function disorders. Methods: This study uses an observational analytic approach with a cross-sectional research design. Eighty-nine patients from patients treated from January 2019 to December 2020 were obtained using total sampling. Patient demographic data were collected, and Spearman's test was performed to see the relationship between LBW and the level of impaired renal function in neonates. Results: During the study, 89 samples were obtained, where the mean body length of the neonates was 44.46 ± 2.22 cm, the ureum range was 6-189 mg/dL, the creatinine range was 0.20 -4.03 mg/dL, mean GFR was known to be 19.01+8.96 ml/min/1.73 m2. The highest number of neonates was in the 34–36-week gestational age group. The average birth weight was 1,964.94 ± 274 g, with a range of 1,500-2,400 g. Most neonates had kidney function of risk (31.5%) and injury (30.3%). Only 15 (16.9%) neonates were not affected. Conclusion: There is a significant relationship between birth weight and the level of impaired kidney function (p < 0.05). The correlation coefficient of 0.217 indicates a weak correlation. There was no relationship (p= 0.061) and no significant correlation between gestational age, low GFR (r= 0.189).


Keywords


neonate, low birth weight, acute kidney injury

Full Text:

PDF

References


Carmody JB, Swanson JR, Rhone ET, et al. Recognition and reporting of AKI in very low birth weight infants. Clin J Am Soc Nephrol. 2014;9(12):2036–43.

Das SK; Choupoo NS; Saikia P; et al. Incidence proportion of acute cor pulmonale in patients with acute respiratory distress syndrome subjected to lung-protective ventilation: a systematic review and meta-analysis. Indian J Crit Care Med. 2017;21(6):364–75.

Dyson A, Kent AL. The Effect of Preterm Birth on Renal Development and Renal Health Outcome. No reviews. 2019;20(12):725–36.

Gomella TL; Cuningham MD; Eyal FG; et al. Neonatology: Management, procedure, On-Call Problems, Disease, and Drug. New York: McGraw-Hill Education; 2013.

Hasanah K, Widajat RR, Mellyana O. Faktor Risiko Prenatal Terhadap Kejadian Penyakit Ginjal Kronik derajat III-V di RSUP Dr. Kariadi Semarang. Sari Pediatr. 2020;22(2):76–82.

Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. New York; 2013.

Koralkar R, Ambalavanan N, Levitan EB, et al. Acute kidney injury reduces survival in very low birth weight infants. Pediatr Res. 2011;69(4):354–8.

Mahayana SAS. Faktor Risiko yang Berpengaruh terhadap Kejadian Berat Badan Lahir Rendah di RSUP Dr. M. Djamil Padang. J Kesehat Andalas. 2015;4(3):664–72.

Nickavar A, Choobdar FA, Mazouri A, et al. Predictive Factors of Acute Renal Failure in the Neonates with Respiratory Distress Syndrome. Iran J Neonatol. 2018;9(1):1–6.

Perwiraningtyas P, Arini NL, Anggraini CY. Analisis Faktor Risiko Tingkat Berat Bayi Lahir Rendah. J Nurs Care. 2020;3(3):212–9.

Permana P, Gede BRW. Analisis Faktor Risiko Bayi Berat Badan Lahir Rendah (BBLR) Di Unit Pelayanan Terpadu (UPT) Kesehatan Masyarakat (Kesmas) Gianyar I Tahun 2016-2017. Intisari Sains Medis. 2019;10(3):674–8.

Pramono MS, Paramita A. Pola Kejadian Dan Determinan Bayi Dengan Berat Badan Lahir Rendah (BBLR) Di Indonesia Tahun 2013. Bul Penelit Sist Kesehat. 2015;18(1):1–10.

Purwanto AD, Chatarina UW. Hubungan Antara Umur Kehamilan, Kehamilan Ganda, Hipertensi Dan Anemia Dengan Kejadian Bayi Berat Lahir Rendah (BBLR). J Berk Epidemiol. 2016;4(3):349–59.

Ruggajo P, Skrunes R, Svarstad E, et al. Familial factors, low birth weight, and development of ESRD: A Nationwide Registry Study. Am J Kidney Dis. 2016;67(4):601–8.

Septiani M, Maria U. Faktor-Faktor yang Berhubungan dengan Kejadian BBLR di Wilayah Kerja Puskesmas Peudada Kabupaten Bireuen. J Berk Epidemiol. 2016;4(2):158–74.

Sulistyorini D, Shinta S. Analisis Faktor-Faktor Yang Memengaruhi Kejadian BBLR Di Puskesmas Perkotaan Kabupaten Banjarnegara. In Semarang: Universitas Muhammadiyah Semarang; 2014.

Viswanathan S, Manyam B, Azhibekov T, et al. Risk factors associated with acute kidney injury in extremely low birth weight (ELBW) infants. Pediatr Nephrol. 2012;27(2):303–11.




DOI: https://doi.org/10.33258/birex.v3i4.2631

Article Metrics

Abstract view : 1 times
PDF - 0 times

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

Creative Commons License
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
 

 

Statcounter for Budapest International Research in Exact Sciences (BirEx Journal)