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Bone Maturnity Delay in Congenital Hypothyroid
Abstract
Congenital hypothyroid (CH) is a Hormonal disorder that can be caused by thyroid gland dysfunction and if not treated early on, will cause serious mental and physical growth disorders. CH is divided into permanent and transient forms which etiologically can be divided into primary, secondary or peripheral. Thyroid dysgenesis is the primary cause and 85% of permanent CH is with abnormalities of thyroid hormone biosynthesis from birth (dishormongeneses). The incidence of dysgenesis accounts for 10-15% of cases. Transient congenital thyroid occurs mostly in infants with preterm birth in low-iodine endemic areas. A study showed a permanent incidence of CH 1: 1500 and transient CH 1: 300 in one of the areas with iodine deficiency in Central Java.Survival analysis showed that the risk of developing mental retardation and delayed physical growth was greater at the age of diagnosis over 1 year.
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Baskin, H. J., Duick, D. S. & Levine, R. A. Thyroid ultrasound and ultrasound-guided FNA: Second edition. Thyroid Ultrasound and Ultrasound-Guided FNA: Second Edition (2008). doi:10.1007/978-0-387-77634-7
B.L. Therrell and C. David-Padilla. Screening newborns for congenital hypothyroidismm : guidance for developing programmes. — Vienna : International Atomic Energy Agency, 2005. p.. WMJ Off. Publ. State Med. Soc. Wisconsin102, 45–50 (2005).
Bringhurst, F. R., Demay, M. B., Krane, S. M. & Kronenberg, H. M. Bone and Mineral Metabolism in Health and Disease. in Harrison’s Principles of Internal Medicine 2454–2465 (2015). doi:10.1017/CBO9781107415324.004
Chen, C.-Y., Lee, K.-T., Lee, C. T.-C., Lai, W.-T. & Huang, Y.-B. Epidemiology and Clinical Characteristics of Congenital Hypothyroidism in an Asian Population: A Nationwide Population-Based Study. J. Epidemiol.23, 85–94 (2013).
Duncan Bassett, J. H. & Williams, G. R. Role of thyroid hormones in skeletal development and bone maintenance. Endocrine Reviews37, 135–187 (2016).
Fogelman, I., Van Der Wall, H. & Gnanasegaran, G. Radionuclide and hybrid bone imaging. Radionuclide and Hybrid Bone Imaging9783642024, (2012).
Gilsanz, V. & Ratib, O. Hand Bone Age Bone Development. Hand Bone Age (2012). doi:10.1007/978-3-642-23762-1
Gittoes, N. J. L. & Sheppard, M. C. Werner and Ingbar’s The Thyroid: A Fundamental and Clinical Text. in The Thyroid: A Fundamental and Clinical Text (eds. Braverman, L. E. & Utiger, R. D.) 831–835 (2005). doi:10.1097/00019616-199707010-00011
Hamdoun, E. et al. The Specter of Untreated Congenital Hypothyroidism in Immigrant Families. Pediatrics137, (2016).
Hashemipour, M. et al. Prevalence of permanent congenital hypothyroidism in Isfahan-Iran. Int. J. Prev. Med.4, 1365–1370 (2013).
Plant, T. M. The hypothalamo-pituitary-gonadal axis. J. Endocrinol.226, T41–T54 (2015).
Rastogi, M. V & LaFranchi, S. H. Congenital hypothyroidism. Orphanet J. Rare Dis.5, 17 (2010).
Rustama, D. S., Fadil, M. R., Harahap, E. R. & Primadi, A. Newborn screening in Indonesia. Southeast Asian J. Trop. Med. Public Health34 Suppl 3, 76–79 (2003).
Simorangkir, E. A., Pintauli, S., and Sudaryati, E. (2020). Relationship between Caries Experience and Food Intake with Stunting Among 6-8-Years Old of Elementary School at Pantai Labu District in 2018. Britain International of Exact Sciences (BIoEx) Journal Vol. 2 (1):313-319.
Srivastava, A. et al. Cretinism Revisited. Indian J. Endocrinol. Metab.16, S336-337 (2012).
DOI: https://doi.org/10.33258/birex.v3i1.1489
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